The pituitary gland produces HGH more than any other hormone. Pituitary cells also called somatotrophin make HGH which is also known as somatotrophin. This is released into the blood for only a few minutes and then taken up into the liver where it is converted into growth factors. The most important of these is Insulin Growth Factor One (IGF-1). It is IGF-1 that is used as a measurement rather than HGH itself as to how much HGH is being secreted by the body and it is IGF-1 that is most directly responsible for the benefits mentioned on this site. Most HGH is secreted into the bloodstream in brief bursts, and most HGH secretion takes place during the early hours of REM (deep) sleep.
Once in the bloodstream, human growth hormone stays there for only a short time, only a few minutes, just long enough to stimulate its uptake into the liver, where it is then converted into growth factors. The most important of these growth factors is called IGF-1, short for Insulin-like Growth Factor-1. IGF-1 is also known as somatomedin C.
Growth hormone exerts its actions either directly or indirectly through its intermediary insulin growth factors (IGF-1) to every organ system of the body. Almost nothing escapes its magic touch. In the same ways that it grows the bones of young children, it increases the size of most organs and tissue. Even the brain is affected. The latest studies in animals show that it can regenerate damaged brain tissue.
It is IGF-1, rather than growth hormone itself, which can vary widely through the day, that is used as a measurement of how much growth hormone is being secreted by the body. IGF-1 is directly responsible for most of the benefits and actions associated with HGH. IGF-1 is 10 times more potent than human growth hormone and is now under investigation as a separate drug for many of the same indications of human growth hormone. Phil Micans of International Aging Systems in London believes that IGF-1 will be the hormone of choice in a few years.






The blueprint of aging is in the DNA under the hood of the telomere", the "clock" at the end of every chromosome that is shortened with each cell division, says noted plastic surgeon and anti-aging researcher, Vincent Giampapa, MD, director of clinical research at the Longevity Institute International in Montclair, New Jersey. To actually reverse aging at the cellular level, we will need a substance that will restore telomere length and like a genie turn old cells into young ones. That is not yet available, although Giampapa believes it will be in less than a decade. Until then, growth hormone and its attendant hormone IGF-1 can do the next best thing, help keep the cell in as healthy a state as possible.
The cell's ability to function depends on the genetic material, the DNA, in the nucleus of the cell which codes for all the proteins, hormones, and enzymes that make the cell run. The DNA is like an army under constant attack from oxygen free-radicals, ultraviolet light, the heat of the body, and other damaging factors. Although the DNA has the ability to repair itself, it falls down on the job with age, a victim of the same aging process that affects the cell. At the same time, damage is accumulating in the energy center of the cell, the mitochondria, which has its own DNA. Up until now, one of the few ways we could limit the damage to the DNA was to take antioxidant supplements such as vitamin C and E to bolster our own defenses.
But, according to Dr. Giampapa and Thierry Hertoghe, MD, a physician specializing in hormone replacement therapy in Brussels, the latest European research shows that human growth hormone and IGF-1 can go further than antioxidants and can do what antioxidants cannot. Human growth hormone and IGF-1 act like carriers to bring the cell the raw materials it needs for renovation and repair. IGF-1 launches the delivery of the nucleic acids, DNA and RNA, right into the cell nucleus, where the DNA resides. The nucleic acids are used to repair damage to the DNA and stimulate cell division. Growth hormone initiates the transport of amino acids, the building blocks of protein, and nucleic acids into the cytoplasm of the cell, the area outside the nucleus. This includes the cell membranes and intracellular organelles, such as the mitochondria. In this way, human growth hormone and IGF-1 don't just minimize the damage to the DNA and cellar structures, they help heal the cell and the DNA. These two hormones actually treat the blueprints of aging.




   Improve heart strength and volume of blood pumped
   Improve Energy
   Improve Sex Life
   Lowers colesterol level
   Improve athletic performance
   Stimulate Quick Recovery from athletic performance or illness
   Improve Mood
   Extend life span in people that use it
   Reduce inflammation, simultaneously support and strengthen joint and connective tissue
   Increase red blood cell and hemoglobin production in animal studies
   Stimulate the production of white blood cells and to improve immunity
   Support muscle protein synthesis
   Stimulate glucose transport in human muscle tissue
   Diminish the rate of protein breakdown
   Shift fuel utilization from carbohydrates to fat, permitting the body to burn more fat
   Assist in the degradation of LDL cholesterol by macrophages
   Improve nitrogen retention and increase sodium excretion
   Improve parathyroid/Vitamin D interaction, producing denser bone matrix
   Enhance production of immune-promoting lymphoid tissue